Publications in peer-reviewed journals:
- Thakur, R., Chattopadhyay, P., Mukherjee, A.K. The wound healing potential of a pro- angiogenic peptide purified from Indian Russell’s viper (Daboia russelii) venom, Toxicon, 165, 78-82, DOI: https://doi.org/10.1016/j.toxicon.2019.04.009 (IF: 3.035).
- Thakur, , & Mukherjee, A.K. Pathophysiological significance and therapeutic applications of snake venom protease inhibitors, Toxicon, 131, 37-47, 2017. DOI: https://doi.org/10.1016/j.toxicon.2017.03.011 (IF: 3.035).
- Thakur, , Kini, S., Kurkalang, S., Banerjee, A., Chatterjee, P., Chanda, A., Mukherjee, A.K. Mechanism of apoptosis induction in human breast cancer MCF-7 cell by Ruviprase, a small peptide from Daboia russelii russelii venom, Chemico-Biological Interactions 258, 297-304, 2016. DOI: https://doi.org/10.1016/j.cbi.2016.09.004 (IF: 5.168).
- Thakur, , Chattopadhyay, P., Ghosh, S.S., Mukherjee, A.K. Elucidation of procoagulant mechanism and pathophysiological significance of a new prothrombin activating metalloprotease purified from Daboia russelii russelii venom, Toxicon 100, 1- 12, 2015. DOI: https://doi.org/10.1016/j.toxicon.2015.03.019 (IF: 3.035).
- Thakur, , Chattopadhyay, P., Mukherjee, A.K. Biochemical and Pharmacological Characterization of a Toxic Fraction and its Cytotoxin-like Component Isolated from Russell’s Viper (Daboia russelii russelii) Venom, Comp Biochem Physiol-Part C, 168, 55-65, 2015. DOI: https://doi.org/10.1016/j.cbpc.2014.12.001 (IF: 4.52).
- Thakur, R., Kumar, , Bose, B., Panda, D., Saikia, D., Chattopadhyay, P., Mukherjee, A.K. A new peptide (Ruviprase) purified from the venom of Daboia russelii russelii shows potent anticoagulant activity via non-enzymatic inhibition of thrombin and factor Xa, Biochimie, 105, 149-158, 2014. DOI: https://doi.org/10.1016/j.cbpc.2014.12.001 (IF: 4.372).
- Mukherjee, A.K., Kalita, B., Thakur, R. Two acidic, anticoagulant PLA2 isoenzymes purified from the venom of monocled cobra Naja kaouthia exhibit different potency to inhibit thrombin and factor Xa via phospholipids independent, non-enzymatic mechanism, PLOS One, 9(8), e101334, DOI: 10.1371/journal.pone.0101334 (IF: 3.752).
- Mukherjee A.K., Chatterjee, S., Majumdar, S., Saikia, D., Thakur, R., Chatterjee, A. Characterization of a pro-angiogenic, novel peptide from Russell’s viper (Daboia russelii russelii) venom, Toxicon, 77, 26-31, DOI: https://doi.org/10.1016/j.toxicon.2013.10.024 (IF: 3.035).
- Mukherjee, A.K.,Rai, S.K., Thakur, R., Chattopadhyay, P, Kar, S. Bafibrinase: A non- toxic, non-hemorrhagic, direct-acting fibrinolytic serine protease from Bacillus strain AS- S20-I exhibits in vivo anticoagulant activity and thrombolytic potency, Biochimie, 94(6), 1300-1308, 2012. DOI: https://doi.org/10.1016/j.biochi.2012.02.027 (IF: 4.372).
- Saikia D., Thakur, R., Mukherjee, A. K. An acidic phospholipase A2 (RVVA-PLA2-I) purified from Daboia russelli venom exerts its anticoagulant activity by enzymatic hydrolysis of plasma phospholipids and by non-enzymatic inhibition of factor Xa in a phospholipids/Ca2+ independent manner, Toxicon, 57(6), 841-850, 2011.DOI: https://doi.org/10.1016/j.toxicon.2011.02.018 (IF: 3.035).
- Mukherjee, A. K., Saikia, D., Thakur, R. Medical and diagnostic application of snake venom proteomes, J Proteins Proteomics,2, 31-40,
B. Book chapters:
- Thakur, R. Characterization of some procoagunt and anticoagulant protein(s) and peptide(s) purified from Indian Russell’s Viper (Daboia russelii russelii) venom, in Summary of Doctoral Theses Vol-X, Das, D. & Saikia, K., eds. Assam College Teachers’ Association, pp. 193-204, 2022. ISBN-978-93-93864-13-0.
- Thakur, , Gogoi, A., Kardong, D., Analyzing the proteolytic and anticoagulant properties of Mesua ferrea leaf extract, in Research in Life Sciences, Begum, M., ed., Aitihya Eshonna (Amulya Kumar Borah), pp. 195-207, 2021. ISBN- 978-81-947823-0-8.
- Thakur, R., & Mukherjee, A.K. A Brief Appraisal on Russell’s Viper Venom (Daboia russelii) Proteinases, in Handbook of Toxinology, Volume: Snake venom, Iganaki, H., Mukherjee, A.K., Rahmy, T.R., Vogel, C-W., eds., Springer, Netherlands, pp. 123-144,
- Thakur, , & Mukherjee, A.K. Pathophysiological significance and therapeutic implications of Russell’s viper venom proteins and peptides affecting blood coagulation, in Snake Venoms and Envenomation: Modern Trends and Future Prospects, Utkin, Y., ed., Nova Science Publishers Inc., New York, pp. 93-114, 2015.
C. List of general articles:
- Thakur, R., An overview of the impact of lockdown due to COVID-19 on domestic violence against women. Prajna, 2021.
- Thakur, R., & Mukherjee, A. K. Snake venom prothrombin activators: their importance and pathophysiological significance, TSI Newsletter, 2(2), 35-38,
- Thakur, R., & Mukherjee, A. K. Focusing on an emergent class of venom component- Thrombin inhibitors: a potential lead compound for cardiovascular drug development, TSI Newsletter, 2(1), 22-24,
- Thakur, R., & Mukherjee, A. K. Venom Therapeutics: A breakthrough in the field of medicine, TSI Newsletter, 2, 8-10,
- List of articles under consideration for publication
- Nath, P., & Thakur, R., Comprehensive GC-MS based metabolite profile and assessment of in vitro antioxidant and anticoagulant properties of Melastoma malabathricum Journal of Biosciences (Under review).
- Kaur, K., Nasreen, S., Kardong, D., Thakur, R. Comparative assessment of the proteolytic and anticoagulant property of Ageratum houstonianum Mill leaf and root extract. (Book Chapter, under review).
- Thakur, R., Kaur, K., Kardong, D. Preliminary investigation of the in vitro fibrinogenolytic and anticoagulant property of Ageratum houstonianum root extract. (Conference Proceedings, under review).
- Nath, P., Thakur, R. GC MS based metabolite profiling and antioxidant activity of methanolic extracts of Mimosa pudica leaves. (Conference Proceedings, under review).
II. PAPERS PRESENTED IN CONFERENCES/SYMPOSIUMS/SEMINARS:
(A) International
- Thakur, R. Evaluating the metabolite profile and ethnopharmacological relevance of Melastoma malabathricum leaf and flower extracts with reference to antioxidant and antithrombotic capacity: A comparative study. 22nd International Conference on the Science of Botanicals and the 7th World Congress on Medicinal and Aromatic Plants, Oxford, MS, USA on 15th -18th April, 2024 (accepted for poster presentation).
- Thakur, R., Role of snake venom procoagulant proteins in venom-induced pathophysiology in bite victims: an updated overview. International Symposium on From Venom Pharmacology to Drug Discovery: National and International Perspective (SNAKESYMP-2024), organized by Institute of Advanced Study of Science and Technology (IASST), Guwahati, India (Invited Speaker)
- Thakur, R., Investigating the therapeutic relevance and metabolite profile of Solanum violaceum Ortega leaf and fruit extracts: A comparative study. 9th India International Science Festival (IISF 2023) -Young Scientist Conference, organized by Government of India’s Ministry of Science and Technology, Ministry of Earth Sciences, Department of Space, Department of Atomic Energy and Government of Haryana in association with Vijnana Bharati, 17th-20th January, 2024, DBT-THSTI-RCB Campus, Faridabad, Haryana, India (Poster Presentation).
- Thakur, R., Nath, P. GC-MS based untargeted metabolite profile, phytochemical analysis and in vitro antioxidant activity of the methanolic extract of Solanum indicum International Bioresource Conclave and Ethnopharmacology Congress (ISES FEC-2023), organized by Institute of Bioresource and Sustainable Development, Imphal and Society for Ethnopharmacology,Kolkata at Imphal, Manipur, India on Feb 24th-26th, 2023 (poster presentation).
- Thakur, R., Dehingia, M., Talukdar, N.C., Khan, M. Variations in gut microbiota and faecal metabolite profile associated with consumption of traditional jaggery based distilled liquor (Chulai) by the tea-tribal population of Assam (India). ADNAT Silver Jubilee Convention and International Symposium on Biodiversity and Biobanking January, 2018, Indian Institute of Technology, Guwahati, Assam, India (Poster presentation).
- Thakur, R., Talukdar, N.C., Khan, M. Effect of a locally-prepared fermented alcoholic beverage from jaggery on the gut bacterial profile of the tea-tribal populations of Assam, 57th Annual Conference of The Association of Microbiologists of India, 24th -27th November, 2016, Gauhati University, Assam, India (Poster presentation-Best Poster Award).
- Thakur, R. & Mukherjee, A.K. Russell’s viper venom proteinases: pathophysiological significance and their therapeutic/diagnostic applications. One Day National Symposium on Snake and Scorpion Envenomation and Therapy: National and International Perspectives, 16th July, 2022, Institute of Advanced Study in Science and Technology, Assam, India (Invited lecture).
- Thakur, , Talukdar, N.C., Khan, M. Microbial characterization and biochemical analysis of a locally-prepared alcoholic beverage consumed by the tea-tribes of Assam and its effect on the gut microbial profile and biochemical biomarkers of the population. R&D Funding Opportunities by SERB-DST: Awareness Workshop for Researchers from North-East Institutions, 14th -15th July, 2022, SERB, GoI and Institute of Advanced Study in Science and Technology (IAAST), Assam, India (Poster presentation-3rd Prize).
- Thakur, , Kaur, K., Kardong, D. Preliminary investigation of the in vitro fibrinogenolytic and anticoagulant property of Ageratum houstonianum root extract. National Seminar on Plant Taxonomy and Traditional Knowledge in the Himalayas and North-East India and Annual Conference of East Himalayan Society for Spermatophyte Taxonomy (EHHST), Department of Botany, Rajiv Gandhi University, Arunachal Pradesh, India. 21st-22nd February, 2022 (Oral presentation, Online).
- Thakur, R. & Bora D.S. Preliminary investigation of the protein profile and enzymatic properties of lesser banded hornet (Vespa affinis) venom. National Seminar on Trends in Biological Sciences and Sustainable Development, Department of Life Sciences, Dibrugarh University, Dibrugarh, Assam, 5th -6th February, 2020 (Oral Presentation).
- Thakur, , Dehingia, M., Talukdar, N.C., Khan, M. Biochemical analysis of a traditional jaggery-based distilled liquor (Chulai) consumed by the tea-tribal population of Assam (India) and its effects on liver function and blood metabolites. 7th Symposium of the DNA Society of India, November, 2017, Institute of Advanced Study in Science and Technology, Assam, India (Poster presentation).
- Thakur, , Kini, S., Kurkalang, S., Banerjee, A., Chatterjee, P., Chanda, A., Mukherjee, A.K. Elucidating the anticoagulant property and anticancer potential of a small peptide purified from Daboia russelii russelii venom. National Seminar on Recent Advances in Snake venom Research and Snakebite therapy, 22nd-24th November, 2016, Tezpur University, Assam, India (Oral presentation-3rd Best Paper Award).
- Thakur, R., Chattopadhyay, P., Mukherjee, A.K. A new prothrombin activator from Indian Russell’s viper (Daboia russelii russelii) venom: characterization and pathophysiological Proceeding of TSICON 2015, 21st-22nd November, 2015, Little Flower Hospital, Angamaly, Cochin, Kerala, India (Oral presentation).
- Thakur, ,Kumar, A., Bose, B., Panda, D, Saikia, D., Chattopadhyay, P., Mukherjee, A.K. Anticoagulant mechanism of a peptide purified from Daboia russelii russelii(Russell’s viper) venom. Proceeding of ‘83rd Annual Meeting of Society of Biological Chemists (India), Evolution: Molecules to Life’, 17th-21st December, 2014, KIIT University, Bhubeneshwar, Odisha, India (Poster presentation).
- Thakur, , Kumar, A., Bose, B., Panda, D, Saikia, D., Chattopadhyay, P., Mukherjee,A.K. Characterization of an anticoagulant peptide with pro-apoptotic properties purified from Daboia russelii russelii(Russell’s Viper) venom. Proceeding of ‘National Seminar on Recent Advances in Biotechnological Research in North East India: Challenges and Prospects’, 27th-29th November, 2014, Tezpur University, Assam, India (Oral presentation-1st Prize ONGC CPBT Young Scientist Award).
- Thakur, R., Rai, S.K., Chattopadhyay, P., Kar, S., Mukherjee, A.K. Characterization of a direct-acting fibrinolytic serine protease (Bafibrinase) from Bacillus strain AS-S20-I: An evaluation of its in vivo toxicity, anticoagulant property and thrombolytic potency. Proceedings of “Recent Advances in Microbial Biotechnology and Molecular Evolution”, 1st-4th March 2013, Tezpur University, Assam, India (Oral presentation).
- Thakur, R. & Mukherjee, A.K. Biochemical and pharmacological properties of a low molecular mass cytotoxin-like molecule purified from Indian Russell’s viper (Daboia russelii russelii) venom. Proceeding of ‘National Conference on Snakebite Management’, 10th-12th December, 2012, University of Mysore and Karnataka State Open University, Karnataka, India (Poster and Oral presentation-Second Best Paper Award for Oral Presentation).
- Thakur, R., Saikia, D., Mukherjee, A.K. Insight into the anticoagulant mechanism of a low molecular weight protein isolated from Indian Russell’s Viper venom. Proceeding of ‘1st National Conference on Animal, Microbial, Plant Toxins & Snakebite Management: Biotoxins in Health & Disease’, 11th-12th December, 2011, IICB and KPC Medical College & Hospital, Kolkata, West Bengal, India (Oral presentation, Invited talk).
- Participated in a National Seminar on “Medicinal Plant and Microbe Diversity and their Pharmaceuticals” held from 19th -21st December 2010, Department of Molecular Biology and Biotechnology, Tezpur University, Assam.
- Thakur, R., & Mukherjee, A.K. Screening for fibrinolytic isoenzymes from venom of Indian Russell’s viper (Daboia russelii russelii). Proceeding of ‘Two-Day National Symposium on Recent Advances in Snake Venom Research and Snakebite Therapy: National and International Perspectives’, 18th-19th December, 2009, Tezpur University, Assam, India (Oral presentation-Young Scientist Award).
- Participated in a UGC sponsored seminar on “Ornamental Fish in North-Eastern Region of India- Its Culture and Maintenance”, 29th- 30th January 2006, D.H.S.Kanoi College, Dibrugarh, Assam, India.